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When you grow to be pregnant whilst taking APTIOM, talk to your overall health care company about registering Together with the North American Antiepileptic Drug (NAAED) Pregnancy Registry. The goal of this registry is to gather information regarding the security of antiepileptic drugs in the course of pregnancy. You may enroll On this registry by calling 1-888-233-2334. Get clinical assistance immediately if you have any in the indicators detailed earlier mentioned.

Before utilizing VALTOCO, tell your healthcare company about all of your medical problems, including if you:

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How will I'm sure if I am addicted? For anyone who is hooked on dihydrocodeine, you could possibly locate it hard to end taking it or feel you must get it far more frequently than required.

diazepam and daridorexant the two increase sedation. Modify Therapy/Monitor Carefully. Coadministration improves chance of CNS depression, which may lead to additive impairment of psychomotor effectiveness and lead to daytime impairment.

sage decreases results of diazepam by pharmacodynamic antagonism. Small/Importance Unfamiliar. Theoretical conversation; some species of sage may well bring about convulsions.

Because of extended-acting metabolite, not deemed a drug of preference during the aged; related to falls

Generic medicines include the exact same Energetic ingredient as the first branded medication and work exactly the same way but might vary in shape or measurement. Most Accord drugs are generic medicines.

Discuss with a physician or pharmacist if you're Uncertain whether or not it's Safe and sound so that you can generate though using dihydrocodeine. GOV.UK has far more information regarding the law on medicines and driving.

phenytoin will reduce the level or impact of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.

The ongoing use of benzodiazepines may perhaps produce clinically substantial Actual physical dependence. The threats of dependence and withdrawal enhance with more time remedy period and better everyday dose. Even though VALTOCO is indicated just for intermittent use, if employed more commonly than proposed, abrupt discontinuation or fast dosage reduction of VALTOCO may perhaps precipitate acute click here withdrawal reactions, that may be everyday living-threatening.

It really is attainable to become hooked on dihydrocodeine. Due to this, your dose will likely be reviewed to be sure you're only owning the quantity you must Management your ache.

Contact a Health care service provider at once if you have any of those signs and symptoms, especially if they are new, even worse, or fret you:

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